Betashares Global Sustainability Leaders ETF

ETHI

ETHI.AX was created on 2017-01-05 by BetaShares. The fund's investment portfolio concentrates primarily on total market equity. The fund aims to track the performance of an index (before fees and expenses) that includes a portfolio of large global stocks identified as Climate Leaders that have also passed screens to exclude companies with direct or significant exposure to fossil fuels or engaged in activities deemed inconsistent with responsible investment considerations.

Actinogen Medical Limited

ACW

Actinogen Medical Ltd. is a clinical stage Australian biotechnology company, which focuses on the development of novel treatments or cognitive impairment associated with neurological, psychiatric, and metabolic diseases due to raised cortisol. The company is headquartered in Sydney, New South Wales. The company went IPO on 2007-10-16. The firm is engaged in the development of a therapy for neurological and neuropsychiatric diseases associated with dysregulated brain cortisol. The firm is engaged in the development of its lead compound, Xanamem, as a therapy for Alzheimer’s Disease, Major Depressive Disorder, Fragile X Syndrome, and other neurological diseases where reducing cortisol inside brain cells could have a positive impact. Xanamem’s mechanism of action is to block the production of cortisol inside cells through the inhibition of the 11B-HSD1 enzyme in the brain. Xanamem is designed to get into the brain after it is absorbed in the intestines upon swallowing its capsule. The company has studied 11B-HSD1 inhibition by Xanamem in approximately 300 volunteers and patients. The firm conducts a series of Phase II studies in multiple diseases to further confirm and characterize Xanamem’s therapeutic potential.

Cogstate Ltd

CGS

Cogstate Ltd. is a global cognitive science company, which engages in delivering software services to optimize the measurement of cognition in clinical trials, academic research, healthcare and brain injury. The company is headquartered in Melbourne, Victoria. The company went IPO on 2004-02-13. Its principal activities are the creation, validation, and commercialization of digital brain health assessments; and design and provision of quality assurance services in clinical trials, focused on the administration, scoring, and recording of conventional brain health assessments. Its segments include Clinical Trials, Healthcare, and Administration. In the Clinical Trials segment, the technology and associated services are used to quantify the effect of disease and of drugs, devices or other interventions on human subjects participating in clinical trials primarily conducted by pharmaceutical, and biotechnology companies. In the Healthcare segment, the technology and associated services are being developed as a tool for primary care physicians and/or hospitals to assess cognitive decline.

Flight Centre Travel Group Limited

FLT

Flight Centre Travel Group Ltd. is engaged in providing travel retailing, wholesaling and corporate travel management services. The company is headquartered in Brisbane, Queensland and currently employs 12,411 full-time employees. The firm's principal activities consist of leisure travel retailing and corporate travel management, plus in-destination travel experience businesses including tour operations, hotel management, destination management companies (DMCs) and wholesaling. Its segments include Leisure, Corporate, and Other. The Leisure segment combines the retail storefront and online brands for retail customers, luxury travel brands Travel Associates and Scott Dunn, independent agents and complementary offerings. The Corporate segment includes the FCM brand, corporate traveler and other corporate customer brands. The Other segment includes Brisbane-based and other support businesses, including Supply, that support the global network and also includes travel management services which incorporate touring, ground-handling and hotels. Its brands include Flight Centre, Aunt Betty, ignite, and Scott Dunn, among others.

Betashares Global Cybersecurity ETF

HACK

HACK.AX was created on 2016-08-30 by BetaShares. The fund's investment portfolio concentrates primarily on theme equity. The fund aims to track the performance of an index (before fees and expenses) that provides exposure to the leading companies in the global cybersecurity sector.